Gonadorelin

Also known as: GnRH, LHRH, Factrel

Sexual HealthFDA Approved (diagnostic)SubcutaneousIntramuscularIntravenous

Synthetic gonadotropin-releasing hormone identical to endogenous GnRH. Used diagnostically and to maintain fertility during testosterone therapy.

Molecular Weight

1182.3 Da

Half-Life

~2-4 minutes

Sequence

pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

Mechanism of Action

Pulsatile administration stimulates LH and FSH release from anterior pituitary. Maintains gonadal function and spermatogenesis when used alongside TRT.

Dosing Protocol

100-200 mcg subcutaneous 2x daily. Used concurrently with TRT to preserve fertility.

Open peptide calculator

Reconstitution

2mg vial + 2mL BAC water = 1000 mcg/mL.

Storage

Lyophilized: -20°C. Reconstituted: 2-8°C, use within 14 days.

Side Effects

●Headache
●Nausea
●Injection site reactions
●Abdominal discomfort

Key Research Findings

●FDA-approved diagnostic for pituitary gonadotroph function
●Maintained spermatogenesis during exogenous testosterone use
●Preserved testicular volume in men on TRT

Research Use Only

This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.