Back to database

Kisspeptin-10

Also known as: Metastin 45-54, KP-10

Sexual HealthInvestigationalSubcutaneousIntravenous

A hypothalamic neuropeptide that stimulates GnRH release, triggering LH and FSH secretion. Being studied for reproductive medicine and as a diagnostic tool.

Molecular Weight

1302.5 Da

Half-Life

~28 minutes

Sequence

Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2

Mechanism of Action

Binds KISS1R (GPR54) on GnRH neurons in the hypothalamus, triggering GnRH pulsatile release. Upstream regulator of the entire HPG axis.

Dosing Protocol

50-100 mcg subcutaneous or IV bolus. Research protocols vary widely.

Open peptide calculator
Reconstitution

5mg vial + 2mL BAC water = 2500 mcg/mL.

Storage

Lyophilized: -20°C. Reconstituted: 2-8°C.

Side Effects
  • ●Headache
  • ●Nausea
  • ●Flushing
  • ●Elevated LH (expected)
Key Research Findings
  • ●Potent stimulator of LH release in both sexes
  • ●Potential IVF trigger alternative to hCG
  • ●Enhanced sexual arousal and brain limbic activation in fMRI studies

Research Use Only

This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.