Melanotan II

Also known as: MT-II, MT2

Skin & HairExperimental / Not FDA approvedSubcutaneous

A synthetic melanocortin peptide analog that stimulates melanogenesis (tanning) and has secondary effects on sexual function and appetite.

Molecular Weight

1024.2 Da

Half-Life

~33 minutes (effects last days)

Sequence

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

Mechanism of Action

Non-selective melanocortin receptor agonist. Activates MC1R (melanogenesis/tanning), MC3R/MC4R (sexual function, appetite suppression).

Dosing Protocol

Loading: 250-500 mcg daily for 1-2 weeks with UV exposure. Maintenance: 500 mcg 1-2x/week.

Open peptide calculator

Reconstitution

10mg vial + 2mL BAC water = 5000 mcg/mL.

Storage

Lyophilized: -20°C. Reconstituted: 2-8°C. Protect from light.

Side Effects

●Nausea (common initially)
●Facial flushing
●Darkened moles
●Spontaneous erections

Key Research Findings

●Significant melanogenesis induction in fair-skinned subjects
●Appetite suppression observed in clinical studies
●Potential photoprotective effects under investigation

Research Use Only

This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.