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MK-677

Also known as: Ibutamoren, Nutrobal

Growth Hormone PeptidesInvestigational (Phase 2 completed)Oral

An orally active, non-peptide growth hormone secretagogue. Mimics ghrelin to stimulate sustained GH and IGF-1 elevation over 24 hours.

Molecular Weight

528.7 Da

Half-Life

~24 hours

Sequence

Non-peptide (small molecule GHS receptor agonist)

Mechanism of Action

Non-peptide ghrelin receptor agonist. Oral bioavailability allows once-daily dosing. Increases GH pulsatility and raises baseline IGF-1 to youthful levels.

Dosing Protocol

10-25 mg oral once daily, typically before bed. No cycling required but monitor blood glucose.

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Reconstitution

Oral compound — no reconstitution needed. Available as capsules or liquid.

Storage

Room temperature. Protect from moisture and light.

Side Effects
  • ●Increased appetite
  • ●Water retention/bloating
  • ●Elevated blood glucose
  • ●Lethargy
  • ●Numbness in hands
Key Research Findings
  • ●Increased IGF-1 to youthful levels in elderly subjects (2-year study)
  • ●Improved sleep quality and REM duration
  • ●Maintained lean body mass during caloric deficit

Research Use Only

This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.