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SNAP-8

Also known as: Acetyl Octapeptide-3

Skin & HairCosmeceuticalTopical

An 8-amino acid peptide that reduces wrinkle depth by inhibiting SNARE complex formation, reducing neurotransmitter release at the neuromuscular junction. A 'topical Botox' concept.

Molecular Weight

1075.2 Da

Half-Life

Topical application (not injected)

Sequence

Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2

Mechanism of Action

Competes with SNAP-25 for SNARE complex positions, reducing vesicle fusion and acetylcholine release at the neuromuscular junction. Reduces muscle contraction and dynamic wrinkles.

Dosing Protocol

3-10% in topical formulations. Applied twice daily to wrinkle-prone areas.

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Reconstitution

Supplied as solution for cosmetic formulation. Not injectable.

Storage

Room temperature. Protect from heat.

Side Effects
  • ●Minimal — occasional mild skin irritation
  • ●Not absorbed systemically
Key Research Findings
  • ●Up to 63% wrinkle depth reduction in 28-day clinical study
  • ●Superior to Argireline (6-amino acid version) in comparative studies
  • ●No systemic absorption — localized cosmetic effect only

Research Use Only

This information is provided for educational and research purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional before using any research compounds.